Dr. Rajeev Agarwal – Leading IVF Specialist & Laparoscopic Surgeon

What is Intra-Ovarian PRP?

What is Intra-Ovarian PRP?

PRP (Platelet-Rich Plasma) therapy is a regenerative treatment that uses the patient’s own blood to extract growth factors and healing components. These growth factors help stimulate tissue repair and rejuvenation. When applied to the ovaries, PRP can activate dormant follicles, enhance egg quality, and improve ovarian function.

The process involves:

  1. Blood Collection – A small amount of blood is drawn from the patient.
  2. PRP Preparation – The blood is processed in a centrifuge to separate the platelet-rich plasma, which contains high concentrations of growth factors.
  3. Injection into the Ovaries – The PRP is injected into the ovaries under mild anesthesia or sedation using ultrasound guidance.

This minimally invasive procedure has been performed over 600 times globally, showing promising success in fertility enhancement.

Who Can Benefit from Intra-Ovarian PRP?

PRP therapy is particularly beneficial for:

  • Women with low ovarian reserve who want to conceive with their own eggs
  • Women over 39 years old looking to improve egg quality before attempting natural conception or IVF
  • Younger women with diminished ovarian function due to early menopause or other reproductive conditions
  • Patients with multiple failed IVF cycles who want to improve their response to treatment
  • Women with irregular cycles or poor ovarian response seeking natural rejuvenation

By improving ovarian function, PRP therapy may even reduce the need for IVF in some cases, allowing women to conceive naturally.

How Does PRP Improve Fertility?

PRP therapy stimulates ovarian tissue by introducing a high concentration of growth factors, which help:

  • Enhance follicle development and increase the chances of producing high-quality eggs
  • Improve ovarian blood flow, delivering more oxygen and nutrients to the developing follicles
  • Activate dormant follicles, which may lead to better ovulation and egg maturation
  • Support hormonal balance, optimizing the ovarian environment for conception

When combined with lifestyle modifications, targeted nutrition, and essential supplements, PRP therapy offers a holistic approach to fertility enhancement.

What to Expect After PRP Therapy?

Most women experience no major side effects after the procedure, as PRP is derived from their own blood. Some may have mild discomfort or bloating for a short period.

Doctors typically monitor ovarian function for a few months after the procedure through hormone tests and ultrasound scans. Many women show improved ovarian response within 2 to 3 months, increasing their chances of pregnancy naturally or through assisted reproductive techniques.

Final Thoughts

Intra-ovarian PRP is a breakthrough in fertility treatment, offering hope to women with declining ovarian function. By enhancing egg quality, stimulating follicle growth, and improving ovarian health, PRP therapy may help women conceive with their eggs—even when conventional treatments have failed.

If you have struggled with low ovarian reserve, IVF failures, or age-related fertility decline, PRP therapy may be a viable option. Consulting a fertility specialist can help determine if this innovative treatment is right for you.

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